Using these tote bags is easy. Just open the top and start putting your things inside. You can use them for work, school, or a day out. When it comes to maintenance, use a soft, damp cloth to wipe off any dirt. Don't use harsh chemicals as they can damage the faux leather. As for the warning, be aware that the product contains chemicals that can be harmful. Avoid direct contact with the chemicals and keep it away from children. If you have any concerns, refer to the link provided in the product description for more information.